In a small village called Amber Stone, right on the outskirts of the Dark Forest, where it's rumored to be lurking with dangerous creatures, a sickly young girl named Lacrima lives together with her family. As alchemists, Lacrima's parents are constantly working on their potions and medicine for the village, which she'd like to help them with but she always receives the same answer: 'you need to rest'. Bored and lonely, Lacrima seeks comfort and adventure in her regular visits to the Dark Forest, where she meets her friend Nox, a mysterious owl creature, and Angis, a non-human alchemist boy who is prone to blushing. One day, Lacrima overhears her parents talking about an essential ingredient needed for their potions: the moonflower, a plant that only blooms in the Dark Forest during full moon nights. Determined to mend her relationship with her parents, Lacrima slips out on the night of the full moon in search of the rare flower.